Document Type : Primary Research paper
Department of Chemistry and Biochemistry, College of Medicine, University of Babylon, Iraq
Asist Prof., Department of Chemistry and Biochemistry, College of Medicine, University of Babylon, Iraq
Prof., College of Medicine, University of Babylon, Iraq
Otitis media is a first intermediary of health care visits across the world. The aims of the present study were to evaluate Galectin-3 , IL-6 and cadmium (Cd) levels in patients with COM. The study population consisted of 100 participants: 50 healthy controls (Group 1) and 50 patients with COM (Group 2). Galectin-3 and IL‑6 were determined using the ELISA, Cd measurement was performed in a graphite furnace atomic absorption spectrophotometer. Galectin-3 and IL‑6 had the highest value in patients with COM (Group 2) compared to the healthy control (Group 1) at (29 ± 9.5 ng/ml vs. 8.6 ± 2.3 ng/ml) and (69.5 ± 22 pg/ml vs. 11.2 ± 2.4 pg/ml), Cd levels were significantl y higher in group 2 than in group 1 at (1.9 ± 0.85 ng/ml vs. 0.5 ± 0.4 ng/ml). Our results could propose that Galectin-3, IL-6 and Cd excess could play a crucial and additive role in the etiopathogenesis of COM. However, further investigations with larger numbers of patients are warranted to determine the exact role of these marker.