Biomedical Applications of Flavonoid Loaded Mesoporous Nanoparticles for the Treatment of Hepatocellular Carcinoma

Document Type : Primary Research paper

Authors

Sri Venkateswara College of Pharmacy, RVS Nagar, Tirupati Road, CHITTOOR – 517127

Abstract

Our research indicates that NLC is the optimal formulation for delivering
anticonvulsant herbal drugs like Convoline, based on the data presented above. Future
research will focus on overcoming the benefits and drawbacks of turning convoline into a
dosage form and determining the precise component responsible for the anticonvulsant
action of convoline. In order to file for a patent after determining the pharmacokinetic and
pharmacodynamic investigations in human volunteers. With the data we selected, we were
able to It was determined that Convoline, a poorly soluble and permeable herbal medicine,
required an unique dosage form carrier molecule (NLC) to ensure its delivery to the
bloodstream. Low soluble and low permeability herbal medications, which fall under BCS
class IV, were specifically engineered to be included into a new NLC carrier. It was
hypothesised that NLC nanocarriers might be used to transport a wide variety of poorly
soluble and poorly permeable herbal drugs.

Volume 11, Issue 1
International Virtual Conference, Recent Materials for, Engineering Applications and Sustainable Environment, December 2020.
May 2020
Pages 570-587