Document Type: Primary Research paper
The effect of acute and chronic exposure of pesticide profenofos on its accumulation and some hematological parameters of the Nile tilapia (Oreochromis niloticus) were studied. The 96 hrs LC50 of profenofos to Nile tilapia was determined to be 0.87 mg/l. No detectable profenofos in aquaria water was observed after 14, 21 and 28 days of trial period and during recovery. Profenofos were accumulated in higher rate fish tissues during the acute exposure. However, during chronic period a gradual increase was observed through 1 to 7 days followed by gradual decrease until it was not detectable at the end of 28 days. Regarding hematology, highly significant increase in WBCs counts during both theacute and chronic exposure to was observed. Highly significant decrease in RBCs counts, Hb content and Hct % was noticed during experimental periods. For most of the recorded data, it showed marked improvement during the recovery period. There was a significant increase in MCHC during both acute andchronic periods which were restored to its normal values by the end of chronic period. During the acute intoxication, MCH and MCV values showed highly significant decrease. Thereafter, MCH and MCV restored its normal level, except MCV on day 7th during the chronic exposure. In conclusion, profenofos exert an alteration of fish hematological parameters and profenofos deposited in their flesh.