Synthesis Of Chitosan Encapsulated Iron Oxide Nanoparticles And Its Biomedical Application

Document Type : Primary Research paper


1 Rearch scholar, Department of Annai velankanni College, Tholayavattum, kanyakumari District-629157, Affliated to Manonmaniam Sundaranar University, Tirunelveli-627012,

2 Associate professor, Department of chemistry, Annai Velankanni College, Tholayavattum, kanyakumari District-629157


The Iron oxide nanoparticles were synthesized by co-precipitation method and consequently stabilized by a chitosan coating. The characterization of synthesized nanoparticles was performed by X-ray diffraction (XRD) and Fourier transforms infrared spectroscopy (FTIR). The observed bands at 500-800 cm-1 in the FTIR spectrum indicated the presence of metal-oxygen (Fe-o) bond whereas band at 1646 cm-1 indicated the presence of amino groups (-NH2) which confirms the CS in the prepared CS-FeO nanoparticles.. The XRD analyses used to prove the synthesized material was magnetite (Fe3O4). The antibacterial activity was assessed by zone of inhibition method against Staphylococcus aureus and Escherichia coli.