Sri Venkateswara College of Pharmacy RVS Nagar, Tirupati Road, CHITTOOR – 517127
Abstract
Recent years have seen a rise in interest in the study of heterocycles (hybrid molecules) due to claims that these compounds exhibit a wide range of pharmacological effects. As a result, it was decided to conduct research on and screen for the biological activities of heterocycles containing thiazolidinedione moieties. The goal of this study was to create novel lead compounds for drug development, namely new anti-diabetic medicines, by synthesising, purifying, characterising, and evaluating substituted thiazolidindione derivatives. This experimental study outlines a technique for synthesising a series of chemicals known as 2-amino (5' (4-sulfonylbenzylidine) 2, 4-thiazolidinedione) sulphonamide derivatives (C1-C5) utilising suitable synthetic processes. Results showed that the yield of the synthesised compounds was between 60% and 79%. The melting point and the presence of a single spot on the TLC confirmed the purity of the produced compounds.
Gunasekaran, D. V., S, D. K., Rajasekhar, S., & Dwarakesh, D. (2019). Novel Design of Thiazolidinediones Derivatives as typical Antidiabetic Agents against Insulin Resistance. Int. J. of Aquatic Science, 10(2), 129-139.
MLA
Dr. V. Gunasekaran; Dr. Kavitha S; S. Rajasekhar; D. Dwarakesh. "Novel Design of Thiazolidinediones Derivatives as typical Antidiabetic Agents against Insulin Resistance". Int. J. of Aquatic Science, 10, 2, 2019, 129-139.
HARVARD
Gunasekaran, D. V., S, D. K., Rajasekhar, S., Dwarakesh, D. (2019). 'Novel Design of Thiazolidinediones Derivatives as typical Antidiabetic Agents against Insulin Resistance', Int. J. of Aquatic Science, 10(2), pp. 129-139.
VANCOUVER
Gunasekaran, D. V., S, D. K., Rajasekhar, S., Dwarakesh, D. Novel Design of Thiazolidinediones Derivatives as typical Antidiabetic Agents against Insulin Resistance. Int. J. of Aquatic Science, 2019; 10(2): 129-139.
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